Clonidine withdrawal [letter]

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Clonidine for Opiate Withdrawal

The abstinence syndrome which follows withdrawal of opiates is the prototype of drug withdrawal reaction and is one of the several factors promoting addiction. Although management of this syndrome is but a small part of treatment of an addict, it is nonetheless an important one. Recent studies have shown that a single dose of Clonidine hydrochloi ide (ARKAMIN) relieves signs and symptoms of opi...

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Effects of clonidine withdrawal: possible mechanisms and suggestions for management.

A severe rebound rise in blood pressure with agitation and insomnia had been noted in five patients when they had previously ceased clonidine (Catapres) This has been shown to be reproducible in these patients and to be associated with a significant increase in urinary catecholamine excretion. The blood pressure can be controlled and the symptoms alleviated promptly by alpha and beta adrenergic...

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18 Clonidine and Lofexidine: New Nonopiate Treatments for Opiate Withdrawal

INTRODUCTION Recent studies (Gold et al, 1978; Washton et al, 1980a) showing that the non-opiate antihypertensive agent, clonidine hydrochloride, suppresses signs and symptoms of opiate withdrawal, have suggested that clonidine and similar drugs might be useful in the clinical management of opiate detoxification. The fact that clonidine is not an opiate drug and does not itself produce addictio...

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Buprenorphine in opiate withdrawal: a comparison with clonidine.

Clinical efficacy of buprenorphine in controlling withdrawal symptoms was compared against clonidine among 44 opiate dependent males. Subjective and objective withdrawal symptoms were assessed by withdrawal rating scales daily for 10 days. The subjects were randomly assigned to fixed dose schedule of either buprenorphine (0.6-1.2 mg per day, sublingually) or clonidine (0.3-0.9 mg per day, oral)...

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Comparing Symptoms of Withdrawal, Rapid Detoxi-fication and Detoxification with Clonidine in Drug Dependent Patients

Abstract Background: Considering the fear of drug addicts from hangover symptoms and the costs of withdrawal treatment and their importance in deciding to withdraw, it is helpful to identify various ways of withdrawal and their effects. This study investigated the withdrawal symptoms of two methods of detoxification with clonidine and rapid detoxification of clonidine with naltrexone....

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ژورنال

عنوان ژورنال: British Journal of Clinical Pharmacology

سال: 1979

ISSN: 0306-5251

DOI: 10.1111/j.1365-2125.1979.tb04726.x